Anti-inflammatory effects of TP1 in LPS-induced Raw264.7 macrophages (2024).
Kim M, An J, Shin SA, Moon SY, Kim M, Choi S, Kim H, Phi KH, Lee JH, Youn UJ, Park HH, Lee CS.
Appl Biol Chem. 67, 16
An Improved In Vitro Blood-Brain Barrier Model for the Evaluation of Drug Permeability Using Transwell with Shear Stress (2023).
Kim J, Shin SA, Lee CS, Chung HJ.
Pharmaceutics. 16(1), 48
DB3 from Antarctic lichen inhibits the growth of B16F10 melanoma cells in vitro and in vivo (2023).
Choi S, Kim H, Shin SA, Kim M, Moon SY, Kim M, Lee S, Lee JH, Park HH, Youn UJ, Lee CS.
Appl Biol Chem. 66, 77
Emerging Immune Checkpoint Molecules on Cancer Cells: CD24 and CD200 (2023).
Moon SY, Han M, Ryu G, Shin SA, Lee JH, Lee CS.
Int J Mol Sci. 24(20):15072.
Comparison of the structure and activity of thioredoxin 2 and thioredoxin 1 from Acinetobacter baumannii (2023).
Chang YJ, Sung JH, Lee CS, Lee JH, Park HH.
IUCrJ. 10(Pt 2), 147-155.
Structural basis for the substrate specificity of an S-formylglutathione hydrolase derived from Variovorax sp. PAMC 28711 (2022).
Hwang J, Kim B, Lee MJ, Nam Y, Youn UJ, Lee CS, Oh TJ, Park HH, Do H, Lee JH.
Biochem Biophys Res Commun. 629:159-164.
Afrormosin exerts an anticancer efect via MAPK and AKT signaling pathways in B16F10 Cells (2022)
Kim H, Han M, Shin SA, An J, Ahn MJ, Lee JH, Park HH, Lee CS.
Appl Biol Chem. 65, 71
Wistin Exerts an Anti-Inflammatory Effect via Nuclear Factor-κB and p38 Signaling Pathways in Lipopolysaccharide-Stimulated RAW264.7 Cells (2022).
An J, Ryu G, Shin SA, Kim H, Ahn MJ, Lee JH, Lee CS.
Molecules. 27(17):5719
Shin SA, Lee JS, Joo BJ, Ryu G, Han M, Kim H, An J, Koo MH, Youn UJ, Lee JH, Park HH, Lee CS (2021)
Anti-cancer effects of lucidadiol against malignant melanoma cells.
Appl Biol Chem. 64, 75
Han M, Ryu G, Shin SA, An J, Kim H, Park D, Lee DH, Lee CS (2021)
Physiological Roles of Apoptotic Cell Clearance: Beyond Immune Functions.
Life (Basel). 11(11), 1141.
Lee SA, Kim D, Min C, Moon B, Lee J, Moon H, Yang S, Lee CS, Lee G, Park D (2021)
Phagocyte Chemoattraction Is Induced through the Mcp-1-Ccr2 Axis during Efferocytosis.
Cells. 10(11), 3115.
An HJ, Kim SH, Yang JW, Kim MH, Baek HJ, Ryu KH, Jeon KN, Lee CS, Choi JY, Song DH (2021)
BAI1 nuclear expression reflects the survival of nonsmoking non-small cell lung cancer patients.
Thorac Cancer. 12(11), 1673-1680.
Jung KH, Kim YG, Kim CM, Ha HJ, Lee CS, Lee JH, Park HH (2021)
FEBS Lett. 595(2), 275-283
Shin SA, Joo BJ, Lee JS, Ryu G, Han M, Kim WY, Park HH, Lee JH, Lee CS (2020)
Phytochemicals as Anti-Inflammatory Agents in Animal Models of Prevalent Inflammatory Diseases.
Molecules. 25(24), 5932
Chun HL, Lee SY, Kim KH, Lee CS, Oh TJ, Park HH (2020)
PLoS One. 15(12), e0242383.
Moon H, Min C, Kim G, Kim D, Kim K, Lee SA, Moon B, Yang S, Lee J, Yang SJ, Cho SK, Lee G, Lee CS, Park CS, Park D (2020)
Crbn modulates calcium influx by regulating Orai1 during efferocytosis.
Nat Commun. 11(1), 5489.
Chun HL, Lee SY, Lee SH, Lee CS, Park HH (2020)
Enzymatic reaction mechanism of cis-aconitate decarboxylase based on the crystal structure of IRG1 from Bacillus subtilis.
Sci Rep. 10(1), 11305.
Hwang J, Jeong CS, Lee CW, Shin SC, Kim HW, Lee SG, Youn UJ, Lee CS, Oh TJ, Kim HJ, Park H, Park HH, Lee JH (2020)
Structural and sequence comparisons of bacterial enoyl-CoA isomerase and enoyl-CoA hydratase.
J Microbiol. 58(7), 606-613.
Rival CM, Xu W, Shankman LS, Morioka S, Arandjelovic S, Lee CS, Wheeler KM, Smith RP, Haney LB, Isakson BE, Purcell S, Lysiak JJ, Ravichandran KS (2019)
Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization.
Nat Commun. 10(1), 4456.
Kwon S, Lee JH, Kim CM, Ha HJ, Lee SH, Lee CS, Jeon JH, So I, Park HH (2019)
Structural insights into the enzyme specificity of a novel ω-transaminase from the thermophilic bacterium Sphaerobacter thermophilus.
J Struct Biol. 208(3), 107395.
Shin SA, Moon SY, Park D, Park JB, Lee CS (2019)
Apoptotic cell clearance in the tumor microenvironment: a potential cancer therapeutic target.
Arch Pharm Res. 42(8), 658-671.
Lee CW, Park SH, Koh HY, Jeong CS, Hwang J, Lee SG, Youn UJ, Lee CS, Park HH, Kim HJ, Park H, Lee JH (2019)
Crystal structure of a transcription factor, GerE (PaGerE), from spore-forming bacterium Paenisporosarcina sp. TG-14.
Biochem Biophys Res Commun. 513(2), 374-379
Kim CM, Ha HJ, Kwon S, Jeong JH, Lee SH, Kim YG, Lee CS, Lee JH, Park HH (2019)
Structural transformation-mediated dimerization of caspase recruitment domain revealed by the crystal structure of CARD-only protein in frog virus 3.
J Struct Biol. 205(2),189-195
Lee CW, Park S, Jeong CS, Lee CS, Hong JW, Park HH, Park H, Park H, Lee JH (2018)
Crystal structure of unphosphorylated Spo0F from Paenisporosarcina sp. TG-14, a psychrophilic bacterium isolated from an Antarctic glacier.
Biodesign. 6(4), 84-91
Moon SY, Shin SA, Oh YS, Park HH, Lee CS (2018)
Understanding the Role of the BAI Subfamily of Adhesion G Protein-Coupled Receptors (GPCRs) in Pathological and Physiological Conditions.
Genes. 9(12), 597.
Shin SA, Moon SY, Kim WY, Paek SM, Park HH, Lee CS (2018)
Structure-Based Classification and Anti-Cancer Effects of Plant Metabolites.
Int J Mol Sci. 19(9), 2651.
Penberthy KK, Rival C, Shankman LS, Raymond MH, Zhang J, Perry JSA, Lee CS, Han CZ, Onengut-Gumuscu S, Palczewski K, Lysiak JJ, Ravichandran KS (2017)
Context-dependent compensation among phosphatidylserine-recognition receptors.
Scientific Reports. 7(1), 14623.
Lee CS, Baek J, Han SY (2017)
The Role of Kinase Modulators in Cellular Senescence for Use in Cancer Treatment
Molecules. 22(9), 1411
Lee CS, Park HH (2017)
Structural aspects of transglutaminase 2: functional, structural, and regulatory diversity
Apoptosis. 22(9), 1057–1068
Hamann J, Hsiao CC, Lee CS, Ravichandran KS, Lin HH (2016).
Adhesion GPCRs as Modulators of Immune Cell Function.
Handb Exp Pharmacol. 234, 329-350.
Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS, MacPherson D (2016).
Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.
Gene and Development. 30(11), 1289-1299
Lee CS, Penberthy KK, Wheeler KM, Juncadella IJ, Vandenabeele P, Lysiak JJ, and Ravichandran KS (2016). Boosting apoptotic cell clearance by colonic epithelial cells attenuates inflammation in vivo
Immunity. 44(4), 807–820.
Lee CS*, Ghim J*, Song P, Suh PG, Ryu SH (2016).
Loss of phospholipase D2 impairs VEGF-induced angiogenesis.
BMB Reports. 49(3), 191-196 (*Co-first authors)
Billings EA, Lee CS, Owen KA, D'Souza RS, Ravichandran KS, Casanova JE (2016)
The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria.
Science Signaling. 9(413), ra14.
Lee CS, Kim JM, Ghim J, Suh PG, Ryu SH (2015)
Cellular Signalling. 27(12), 2363-70.
Fond AM*, Lee CS*, Schuman IG, Kiss. RS, Ravichandran KS (2015).
Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.
Journal of Clinical Investigation.125(7), 2748-58. (*Co-first authors)
Ghim J*, Moon JS*, Lee CS*, Lee J, Song P, Lee A, Jang JH, Kim D, Yoon JH, Koh YJ, Chelakkot C, Kang BJ, Kim JM, Kim KL, Yang YR, Kim Y, Kim SH, Hwang D, Suh PG, Koh GY, Kong YY, Ryu SH (2014).
Endothelial deletion of phospholipase D2 reduces the hypoxic response and pathological angiogenesis.
Arteriosclerosis, Thrombosis, and Vascular Biology. 34(8), 1697-1703. (*Co-first authors)
**This work was highlighted as the cover story of journal.
Lee CS*, Ghim J*, Jang JH*, Jeon H, Suh PG, and Ryu SH (2014).
Emerging roles of phospholipase D in pathophysiological signaling (Book chapter).
Phospholipases in Health and Disease, Advances in Biochemistry in Health and Disease. 10(22), 359-379. (*Co-first authors)
Lee DH, Lee CS, Kim DK, Ae JE, Lee TH (2014).
Digitoxin sensitizes glioma cells to TRAIL-mediated apoptosis by up-regulation of death receptor 5 and down-regulation of survivin.
Anti-Cancer drugs. 25(1), 44-52.
Lee CS, Ryu SH (2013).
PLD2 (phospholipase D2).
Atlas Genet Cytogenet Oncol Haematol. 17(9), 633-639.
Hochreiter-Hufford AE, Lee CS, Kinchen JM, Sokolowski JD, Arandjelovic S, Call JA, Klibanov AL, Yan Z, Mandell JW, Ravichandran KS (2013).
Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion.
Nature. 497(7448), 263-267.
**This work was highlighted in news and views of Nature.
Yu SF, Baylies MK. “Cell biology: Death brings new life to muscle”. Nature (497,196–197).
Kim JM, Shin HI, Cha SS, Lee CS, Hong BS, Lim S, Jang HJ, Kim J, Yang YR, Kim YH, Yun S, Rijal G, Lee-Kwon W, Seo JK, Gho YS, Ryu SH, Hur EM, Suh PG (2012).
DJ-1 promotes angiogenesis and osteogenesis by activating FGF receptor-1 signaling.
Nature Communications. 3, 1296.
Park JB*, Lee CS*, Jang JH, Ghim J, Kim YJ, You S, Hwang D, Suh PG, Ryu SH (2012).
Phospholipase signalling networks in cancer.
Nature Reviews Cancer. 12(11), 782-792. (*Co-first authors)
Jang JH*, Lee CS*, Hwang D, Ryu SH (2012).
Understanding of the roles of phospholipase D and phosphatidic acid through their binding partners.
Progress in Lipid Research. 51(2), 71-81. (*Co-first authors)
Jeon H, Kwak D, Noh J, Lee MN, Lee CS, Suh PG, Ryu SH (2011).
Phospholipase D2 induces stress fiber formation through mediating nucleotide exchange for RhoA.
Cellular Signalling. 23(8), 1320-1326.
Lee CS, Ryu SH (2011).
PLD1 (phospholipase D1, phosphatidylcholine-specific).
Atlas Genet Cytogenet Oncol Haematol. 15(6), 515-519.
Lee CS, Kim KL, Jang JH, Choi YS, Suh PG, Ryu SH (2009).
The roles of phospholipase D in EGFR signaling.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1791(9), 862-868.
Lee MN, Ha SH, Kim J, Koh A, Lee CS, Kim JH, Jeon H, Kim DH, Suh PG, Ryu SH (2009).
Glycolytic flux signals to mTOR through GAPDH-mediated regulation of Rheb.
Mol Cell Biol. 29(14), 3991-4001.
Yoon JH, Yea K, Kim J, Choi YS, Park S, Lee H, Lee CS, Suh PG and Ryu SH (2009).
Comparative proteomic analysis of the insulin-induced L6 myotube Secretome.
Proteomics. 9(1), 51-60.
Lee CS, Kim IS, Park JB, Lee MN, Lee HY, Suh PG, and Ryu SH (2006).
The phox homology domain of phospholipase D activates dynamin GTPase activity and accelerates EGFR endocytosis.
Nature cell biology 8(5), 477-484.
**This work was highlighted in news and views of Nature cell biology.
Hinshaw JE. “Filling the GAP for dynamin”, Nature cell biology (8(5), 432 - 433).
Kim SH, Kim YH, Shin KJ, Oh YS, Lee CS, Kang KO, Ryu SH, and Suh PG (2005).
2,2',4,6,6'-Pentachlorobiphenyl-induced apoptosis is limited by cyclooxygenase-2 induction.
Toxicol Sci. 83(2), 397-404.
Park JB, Lee CS, Lee HY, Kim IS, Lee BD, Jang IH, Jung YW, Oh YS, Han MY, Jensen ON, Roepstorff P, Suh PG, and Ryu SH (2004).
Regulation of phospholipase D2 by GTP-dependent interaction with dynamin.
Adv Enzyme Regul. 44(1), 249-264.
Cho CH, Lee CS, Chang M, Jang IH, Kim SJ, Hwang I, Ryu SH, Lee CO, and Koh GY (2004).
Localization of VEGFR-2 and PLD2 in endothelial caveolae is involved in VEGF-induced phosphorylation of MEK and ERK.
Am J Physiol (Heart Circ Physiol). 286(5), H1881-1888.
Yoon MJ, Cho CH, Lee CS, Jang IH, Ryu SH, and Koh GY (2003).
Localization of Tie2 and phospholipase D in endothelial caveolae is involved in angiopoietin-1-induced MEK/ERK phosphorylation and migration in endothelial cells.
Biochem Biophys Res Commun. 308(1), 101-105.
Jang IH, Lee S, Park JB, Kim JH, Lee CS, Hur EM, Kim IS, Kim KT, Yagisawa H, Suh PG, and Ryu SH (2003).
The direct interaction of phospholipase C-gamma 1 with phospholipase D2 is important for epidermal growth factor signaling.
J Biol Chem. 278(20), 18184-18190.
Han JM, Kim Y, Lee JS, Lee CS, Lee BD, Ohba M, Kuroki T, Suh PG, and Ryu SH (2002).
Localization of phospholipase D1 to caveolin-enriched membrane via palmitoylation: implications for epidermal growth factor signaling.
Mol Biol Cell. 13(11), 3976-3988.
Lee S, Kim JH, Lee CS, Kim JH, Kim Y, Heo K, Ihara Y, Goshima Y, Suh PG, and Ryu SH (2002).
Collapsin response mediator protein-2 inhibits neuronal phospholipase D(2) activity by direct interaction.
J Biol Chem. 277(8), 6542-6549.
Lee CS, Bae YS, Lee SD, Suh PG, and Ryu SH (2001).
ATP-induced mitogenesis is modulated by phospholipase D2 through extracellular signal regulated protein kinase dephosphorylation in rat pheochromocytoma PC12 cells.
Neurosci Lett. 313(3), 117-120.